Nutraceutical developer Monteloeder explained the research and development of its new ingredient, supported by a recent clinical study.
In a July 30, 2024 press release, Monteloeder, a subsidiary of SuanNutra, announced its new botanical composition BeRelief, designed for relieving musculoskeletal pain such as back aches. The ingredient is a combination of extracts from ashwagandha, rosemary, and sesame. As traditional remedies and medicines, Aswagandha is used for improving sleep and mood, rosemary is used for relieving both muscle and joint pain, and sesame is used for relieving pain from inflammatory conditions.
Research for developing BeRelief involved assessing 50,000 natural compounds and selecting ones based on their molecular interactions with receptors involved in the perception of discomfort and pain.
"As a research-driven company, we are inspired by nature and traditional herbal medicine to create botanical solutions that can help people feel better," stated Maria Ángeles Gutiérrez Montero, Marketing Director of SuanNutra, in the press release. "We are combining the wisdom of Eastern botanical medicine with modern science and 'big data' to support this innovative solution and provide a holistic approach to total well-being."
The ingredient was developed with the assistance of machine learning, and was also tested in a randomized double-blind controlled study, which was recently published in Frontiers in Nutrition1. The 12-week trial involved 135 participants with back and neck pain. Two groups of the participants received doses of BeRelief – either 400mg or 800mg – and both demonstrated a reduction in their discomfort, by 56% in the group with the lower dose and by 59% in the group with the higher dose. The relief was reported to be sustained, and BeRelief users also reported improved mood and sleep.
"Discomfort and soreness can be debilitating and significantly impact a person's quality of life," explained Gutiérrez Montero. "Developing a natural ingredient can help enhance quality of life by reducing or alleviating pain. In today's sedentary, stress-filled, and sleep-deprived lifestyles, discomfort and pain are increasingly common. Prolonged sitting, repetitive activities, occasional stress peaks, and lack of sleep can lead to issues like muscle tension, joint pain, and headaches, which worsen over time."
Support for the development of BeRelief came from Center for Technological Development and Innovation (CDTI Innovation) and was financed in part by the European Union's FEDER funds.
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