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The future looks encouraging for antioxidant research, despite some new articles that questioned the effectiveness of antioxidant supplements. 

Radical Solutions

Consumers and food companies understand that dietary fiber provides a healthy, sustained glycemic response to glucose spikes.

Fiber is Fashionable, Again

The new line is made up of three gummies and one softgel that are formulated to meet stringent EU-Organic certification criteria, and target women’s health, metabolic health, and heart health.

Sirio Pharma launches line of ready-to-market organic gummies and softgels called PureOrganix

Sirio Pharma has announced that its Ubidecarenone Chewable Gels have been added to the United States Pharmacopoeia (USP) monograph. 

Sirio Pharma sets USP reference standard for ubidecarenone chewable gels

SourceOne Global Partners has announced a partnership with Qualitas Health Inc., (dba iwi life) to introduce the company’s trademarked AlmegaPL microalgae omega-3 ingredient to the global marketplace. 

SourceOne Global Partners to distribute Qualitas Health’s microalgae omega-3 ingredient globally

A systematic review examined studies on the effects of two types of Vitamin E for improving heart health.

Tocotrienol vs. Tocopherol: A Systematic Review Highlights Superior Efficacy in Heart Health Improvement

Researchers reviewed 11 studies and found that there was no difference in the incidence of bleeding events between patients receiving omega-3 PUFAs and those not receiving them. High dose EPA consumption was associated with an elevated but modest risk. 

Meta-analysis does not find increased risk of bleeding events from omega-3 PUFA consumption

Nils Hoem of Aker BioMarine explains the connection between liver and heart health

 spoke with Aker BioMarine’s chief scientist Nils Hoem about the connection between liver health and heart health, and how krill oil fits into this relationship. The key to this connection is lipids. It is well understood that high levels of cholesterol, specifically low-density lipoprotein (LDL), can lead to a higher risk of heart disease and stroke, building up in the walls of your blood vessels. By contrast, so-called good cholesterol, high-density lipoprotein (HDL), absorbs cholesterol in the blood and carries it back to the liver where it is flushed from the body.

“It's the liver that is taking care of the packaging of the lipid particles,” says Hoem. “The liver is also particular in that it stores fat in its own cells in what are called hepatocytes. Every other storage of fat happens within specialized cells called adipocytes, so the liver is really a factory where lipids are taken care of and where the lipids that it sends out to the rest of the body are taken care of and [ensures] the lipid particles have the right composition.”

An unhealthy liver can negatively impact cardiovascular health. Non-alcoholic fatty liver disease, which is a buildup of too much fat in the liver common in overweight or obese people, affects about 25% of the world’s population, and about 100 million people in the U.S.

 Hoem explains that non-alcoholic fatty liver disease significantly increases one’s risk of developing metabolic syndrome, which is a cluster of conditions such as high blood pressures, high blood sugar, excess body fat, and high cholesterol or triglyceride levels that increase your risk of heart disease, stroke and type 2 diabetes.

Changing the course of one’s non-alcoholic fatty liver disease can be done through dietary means if caught early enough, and one way to do so, says Hoem, is to increase one’s intake of phospholipids and long-chain omega-3 fatty acids, namely EPA and DHA. Krill oil is the phospholipid form of EPA and DHA, that is also rich in phosphatidylcholine, which is a source of choline found naturally in the body.

“Choline has a direct effect on how much lipids are stored within the adipocytes,” says Hoem. “The body will have opportunities for storing fat either in the liver or out in the adipocytes, so there needs to be a balance.” Poor levels of choline in the diet can increase one’s risk of developing non-alcoholic fatty liver disease because phosphatidylcholine carries fat away from the liver, and not enough choline can lead to too much fat being stored in the liver.

LDL and HDL Cholesterol: “Bad” and “Good” Cholesterol. Centers for Disease Control and Prevention.May 16, 2023. Accessed November 14, 2023. 

https://www.cdc.gov/cholesterol/ldl_hdl.htm#:~:text=High%20levels%20of%20LDL%20cholesterol,flushes%20it%20from%20the%20body

Nonalcoholic fatty liver disease. Mayo Clinic. October 6, 2023. Accessed November 14, 2023. 

https://www.mayoclinic.org/diseases-conditions/nonalcoholic-fatty-liver-disease/symptoms-causes/syc-20354567

Metabolic syndrome. Mayo Clinic. May 6, 2021. Accessed November 14, 2023. 

https://www.mayoclinic.org/diseases-conditions/metabolic-syndrome/symptoms-causes/syc-20351916

The Nutrition Source: Choline. Harvard T.H. Chan School of Public Health. March 2023. Accessed November 14, 2023. 

https://www.hsph.harvard.edu/nutritionsource/choline/#:~:text=There%20is%20a%20link%20between,to%20store%20too%20much%20fat

Videos

At this year’s SupplySide West, Nutritional Outlook spoke with Aker BioMarine’s chief scientist Nils Hoem about the connection between liver health and heart health, and how krill oil fits into this relationship. 

Heart Health

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