Three Glutathione Benefits You May Not Know About

Danielle Citrolo

Glutathione is becoming more and more well known among consumers, but some of us are still strangers to this extremely powerful antioxidant. It supports our body’s natural defenses, bolstering our immune system’s natural defense network by fortifying natural killer cells (NK cells).

So while some of us are aware of the power of glutathione, there may still be some benefits that aren’t on your radar yet. Here’s three benefits that you and your consumers could benefit from knowing about:

1. Reduces Oxidative Stress

Cellular metabolism, the process by which cells make energy to perform life processes, involves the chemical breakdown of oxygen molecules. This reaction causes the production of unstable molecules called free radicals. If left un-neutralized, free radicals accumulate in the body, causing oxidative stress, a type of cell damage that can harm DNA, proteins, and other vital molecules. Oxidative stress is associated with the development of immune disorders, aging, and numerous diseases such as rheumatoid arthritis, cataracts, and cancer.

Studies have shown that the body’s natural defenses against free radicals can be supported by increasing levels of glutathione in the body. In a 2023 study analyzing the metabolism of glutathione and its possible effects in cancer therapy, it was revealed that glutathione has a potential protective role for cancer cells and should be considered under medical supervision.

2. May reduce respiratory disease symptoms

Certain respiratory diseases such as asthma and cystic fibrosis have been treated with the medication N-acetylcysteine. It functions as an inhalant, helping to thin mucus and reduce inflammation. According to a study analyzing the role of N-acetylcysteine supplements, N-acetylcysteine was shown to be a byproduct of glutathione.

3. Reduces cell damage in alcoholic and nonalcoholic fatty liver disease

Glutathione supports the body’s detoxification process by aiding the function of our liver, kidneys, GI tract, and intestines — our body’s major detoxification pathways. But when it comes to the liver, cell death can become exacerbated by a deficiency in antioxidants, including glutathione. Unfortunately, this can lead to fatty liver disease — also known as hepatic steatosis —in those who misuse alcohol and those who don’t.

In a study analyzing both alcohol and non-alcohol related fatty liver diseases, it was noted that glutathione was effective when given to individuals in high doses. Reductions in malondialdehyde, a marker of cell damage in the liver, were also reported among study participants.

Orally administered glutathione paired with proactive lifestyle changes revealed to have had positive effects on individuals with nonalcoholic fatty liver disease in another study. This particular study provided glutathione in supplement form in a dose of 300 milligrams per day for four months.

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