Study finds that a citrus flavonoid blend from Ingredients by Nature may attenuate intestinal dysbiosis in prediabetics

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A recent study¹ found that a patented citrus flavonoid blend from Ingredients by Nature, called Eriomin, may attenuate intestinal dysbiosis. In the study, 29 prediabetic patients were randomized to receive either 200 mg per day of Eriomin or placebo for 12 weeks. After conducting a profile of microorganisms, researchers observed a change in microbial composition following the consumption of the citrus flavonoid blend. Specifically, there was a lower growth of Firmicutes, and less abundance of the Lachnospiraceae family, while the family Ruminococcaceae increased and Blautia genus declined. Subjects taking Eriomin also experienced a 6% reduction in hyperglycemia and a 22% increase in GLP-1 blood levels.

The decline in Blautia was positively correlated the reduction of hyperglycemia. According to the researcher, the Ruminococcaceae family is associated with the fermentation of complex carbohydrates such as fibers and resistant starches, as well as polyphenols, to produce short chain fatty acids, some of which can strengthen intestinal barrier and reduce systemic low-grade inflammation associated with glucose intolerance and diabetes.

“These results further demonstrate Eriomin’s potential for those who need support in maintaining healthy blood glucose levels,” said Rob Brewster, president of Ingredients by Nature, in a press release. “This is the third published human clinical trial backing Eriomin. We are thrilled to share this news with the industry and will continue investigating Eriomin’s powerful effects for numerous health benefits.”

Reference

Ramos F.M.M.; Ribeiro, C.B.; Cesar, T.B.; Milenkovic, D.; Cabral, L.; Noronha, M.F.; Sivieri, K. Lemon Flavonoids Nutraceutical (Eriomin®) Attenuates Prediabetes Intestinal Dysbiosis: A Double-Blind Randomized Controlled Trial. Food Science & Nutrition. 2023, Article ASAP. DOI: 10.1002/fsn3.3654