Ponce De Leon Health launches an innovative supplement to “resist” biological aging

Photo © iStockphoto.com/mevans 

Ponce De Leon Health (Fernandina Beach, FL) has launched a product under that brand name Rejuvant called LifeTabs, a dietary supplement with formulations for men and women designed to “resist aging.” The product contains a patent pending formulation of Calcium Alpha-Ketoglutarate (brand name LifeAKG), which is generally recognized as safe.

Rejuvant LifeTabs come in formulations for men and women, and was developed in collaboration with Brian Kennedy, PhD, of the Buck Institute for Research on Aging, to modulate pathways associated with healthy aging, including DNA de-methylation, potentially decreasing biological age. DNA methylation, the current gold-standard for determining human biological age, is an epigenetic mechanism that occurs by the addition of methyl groups to DNA, thereby often modifying the function of the genes and affecting gene expression over time. The product also comes with a non-invasive DNA methylation test to measure biological age versus chronological age.

According to its press release, a scientific paper is pending publication in which the researchers at the Buck Institute were able to postpone the onset of frailty in mammals. The results were presented at the Nature Conference 2019: Ageing, Health, and Rejuvenation, in Rotterdam, the Netherlands, June 23-26. There, the researchers stated: “[if] translated to humans, this effect would be an ideal outcome, extending lifespan but more importantly reducing the debilitating period of functional decline and disease management that plague many aging individuals…In humans, plasma AKG levels decline 10 folds between the ages of 40 and 80. The molecule is not available in the human diet, making direct supplementation the only feasible route to restore levels."

"Many companies looking to enhance and extend healthspan have developed products that simply miss the mark," stated Tom Weldon, CEO of Ponce De Leon Health, in a press release. "Their products lack the scientific data to show an actual delay in frailty and an increase in healthspan, while Rejuvant contains a safe, anti-aging powerhouse in a patent pending ingredient called LifeAKG, potentially helping people live longer and healthier by hindering DNA methylation and reducing sources of oxidative stress caused by senescent cells."