Combination of Boswellia serrata and type II collagen may support joint pain and stiffness, says recent study

Photo © iStockphoto.com/monkeybusinessimages

A recent study¹ found that supplementation with a formula that combines Boswellia serrata and a native type II collagen, Collavant n2 from Bioiberica (Barcelona, Spain), may support symptoms of osteoarthritis. In the multicenter, observational study, 40 subjects with knee osteoarthritis were instructed to take the supplement once daily for three months. Subjects visited their respective study center on day 0, day 5, day 15, day 30, day 60 and day 90 for evaluation. Results showed that compared to baseline, subjects saw significant reductions in pain and stiffness, as well as improvements in physical function. Reductions in pain scores were observed as early as the second visit based on visual analogue scale scores. No significant side effects were reported.

“Boswellia serrata is considered a potent anti-inflammatory and anti-arthritic herbal extract, that may help to improve pain and physical function in patients with osteoarthritis. Likewise, Collavant n2 has demonstrated benefits in joint health at only 40mg per day. This makes both ingredients attractive options for innovation in the mobility space. In fact, the number of product launches featuring collagen and herbal combinations has grown at a CAGR of 25% since 2017, and those containing native type II collagen and Boswellia serrata specifically have risen at a CAGR of 71% since 2018,” said Daniel Martínez Puig, head of R&D Human Health, Bioiberica.

“Usually, when used alone, the benefits of Collavant n2 are experienced within 1-2 months, so we were very interested when our strategic partner in India shared the results of this study with us, showing that when used in combination with this herbal extract, the benefits were felt in just five days,” Puig adds. “This signifies that specific ingredients can bring unique and important advantages, like enhanced efficacy, when brought together in one solution. These findings therefore present an exciting opportunity for formulators looking to explore new combinations with trending ingredients, like native type II collagen and herbal extracts, and show the potential to unlock solutions that deliver novel benefits.”

Reference

1. Jain AV et al. “AflaB2and osteoarthritis: a multicentric, observational, post-marketing surveillance study in Indian patients suffering from knee osteoarthritis.” International Journal of Research in Orthopaedics, vol. 7, no. 1 (January 2021): 110-115