Blue California, Conagen commercialize fermentation-derived NMN ingredient for healthy aging, energy

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Ingredients supplier Blue California (Rancho Santa Margarita, CA) and Massachusetts-based biotech company Conagen are together commercializing a high-purity, fermentation-derived nicotinamide mononucleotide (NMN) ingredient that they say stands out from current NMN ingredients produced by chemical synthesis.

NMN is a precursor to nicotinamide adenine dinucleotide (NAD+), the coenzyme present in all living cells, and is critical for mitochondrial function. Increased intracellular levels of NAD+ boost energy production and improve cellular health but levels decline dramatically with age. Replenishing NAD+ with its precursor NMN may combat age-related degeneration and increase healthy lifespan. In the market, NMN supplements are promoted for supporting brain health, vitality, heart health, metabolic health, and even cosmetic benefits.

“Our fermentation-derived offering is well positioned to capitalize on the growing recognition of NMN as an important ingredient in the food and supplement spaces,” chief science officer at Blue California, Priscilla Samuel, PhD, said in a press release. “NMN is a well-known molecule in the longevity research community, and emerging research also suggests potential applications for immune health as well as sports nutrition.”

The companies say their ingredient is a cost-effective option for dietary supplement and functional food and beverage manufacturers. “Blue California’s fermentation-derived NMN opens new opportunities for producers to consider consumers’ health more holistically while acquiring a closer-to-nature position,” the press release states.

Conagen’s other longevity ingredients include ergothioneine and pyrroloquinoline quinone, all made using proprietary fermentation processes.